316 citations · 1.2k across the 27 of their papers we have counts for
8 papers · 1 filter
Stress-dependent amplification of active forces in nonlinear elastic media
Pierre Ronceray, Chase Broedersz, Martin Lenz
The production of mechanical stresses in living organisms largely relies on localized, force-generating active units embedded in filamentous matrices. Numerical simulations of disc…
Extensile actomyosin?
Martin Lenz
Living cells move thanks to assemblies of actin filaments and myosin motors that range from very organized striated muscle tissue to disordered intracellular bundles. The mechanism…
Cell contraction induces long-ranged stress stiffening in the extracellular matrix
Yu Long Han, Pierre Ronceray, Guoqiang Xu +5
Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can signific…
A Reaction-Diffusion Model of the Cadherin-Catenin System: A Possible Mechanism for Contact Inhibition and Implications for Tumorigenesis
Markus Basan, Timon Idema, Martin Lenz +2
Contact inhibition is the process by which cells switch from a motile growing state to a passive and stabilized state upon touching their neighbors. When two cells touch, an adhesi…
Geometrical origins of contractility in disordered actomyosin networks
Martin Lenz
Movement within eukaryotic cells largely originates from localized forces exerted by myosin motors on scaffolds of actin filaments. Although individual motors locally exert both co…
Contractile units in disordered actomyosin bundles arise from F-actin buckling
Martin Lenz, Todd Thoresen, Margaret L. Gardel +1
Bundles of filaments and motors are central to contractility in cells. The classic example is striated muscle, where actomyosin contractility is mediated by highly organized sarcom…