14 papers
SC-TauPath: A Structural Connectivity Attribution Framework for Mapping Tau Propagation Pathways in Alzheimer's Disease
Jing Zhang, Norman Scheel, Minheng Chen +5
Understanding how structural connections are associated with tau propagation in Alzheimer's disease (AD) remains a central open question, yet existing computational models either r…
Vibe Medicine: Redefining Biomedical Research Through Human-AI Co-Work
Zihao Wu, Steven Xu, Bowen Chen +8
With the emergence of large language models (LLMs) and AI agent frameworks, the human-AI co-work paradigm known as Vibe Coding is changing how people code, making it more accessibl…
Evaluation of OpenAI o1: Opportunities and Challenges of AGI
Tianyang Zhong, Zhengliang Liu, Yi Pan +73
This comprehensive study evaluates the performance of OpenAI's o1-preview large language model across a diverse array of complex reasoning tasks, spanning multiple domains, includi…
GP-GPT: Large Language Model for Gene-Phenotype Mapping
Yanjun Lyu, Zihao Wu, Lu Zhang +11
Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits a…
Bridging Brain Connectomes and Clinical Reports for Early Alzheimer's Disease Diagnosis
Jing Zhang, Xiaowei Yu, Minheng Chen +8
Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in pract…
Domain-Adaptive Diagnosis of Lewy Body Disease with Transferability Aware Transformer
Xiaowei Yu, Jing Zhang, Tong Chen +8
Lewy Body Disease (LBD) is a common yet understudied form of dementia that imposes a significant burden on public health. It shares clinical similarities with Alzheimer's disease (…