System- and Sample-agnostic Isotropic 3D Microscopy by Weakly Physics-informed, Domain-shift-resistant Axial Deblurring

Jiashu Han, Kunzan Liu, Keith B. Isaacson +3

Three-dimensional (3D) subcellular imaging is essential for biomedical research, but the diffraction limit of optical microscopy compromises axial resolution, hindering accurate 3D…