8 papers
Activity driven buckling and pattern formation in shells of oriented solids
Niels de Graaf Sousa, Varun Venkatesh, Amin Doostmohammadi
We investigate shells of active oriented solid, materials in which orientationally ordered active particles are embedded in a deformable elastic surface. Focusing on cylindrical ge…
Epithelia Realize Nematopolar Topological Defect Structures
Tianxiang Ma, Niels de Graaf Sousa, Valeriia Grudtsyna +2
We introduce a shape-based polar order parameter that captures the structural asymmetry of cells within epithelial monolayers. By combining bright-field imaging and traction force…
Cell-induced wrinkling patterns on soft substrates
Aleksandra Ardaševa, Varun Venkatesh, Daiki Matsunaga +2
Cells exert traction forces on compliant substrates and can induce surface instabilities that appear as characteristic wrinkling patterns. Here, we develop a mechanical description…
A spectrum of p-atic symmetries and defects in confluent epithelia
Lea Happel, Griseldis Oberschelp, Anneli Richter +4
Topological defects provide a unifying language to describe how orientational order breaks down in active and living matter. Considering cells as elongated particles confluent, epi…
Density-Velocity Relation Is Scale-Dependent in Epithelial Monolayers
Hengdong Lu, Tianxiang Ma, Amin Doostmohammadi
The relationship between cell density and velocity is often assumed to be negative, reflecting crowding-induced suppression of movement. However, observations across systems reveal…
Cellular Flow Architecture Exposes the Hidden Mechanics of Biological Matter
Tianxiang Ma, Valeriia Grudtsyna, Robin V. Bölsterli +1
Understanding how biomechanical reorganization governs key biological processes, such as morphogenesis and development, requires predictive insights into stress distributions and c…