2 papers
q-bio.QM2025
De novo peptide sequencing rescoring and FDR estimation with Winnow
Amandla Mabona, Jemma Daniel, Henrik Servais Janssen Knudsen +7
Machine learning has markedly advanced de novo peptide sequencing (DNS) for mass spectrometry-based proteomics. DNS tools offer a reliable way to identify peptides without relying…
q-bio.QM2024
Protein binding affinity prediction under multiple substitutions applying eGNNs on Residue and Atomic graphs combined with Language model information: eGRAL
Arturo Fiorellini-Bernardis, Sebastien Boyer, Christoph Brunken +4
Protein-protein interactions (PPIs) play a crucial role in numerous biological processes. Developing methods that predict binding affinity changes under substitution mutations is f…