47 citations · 104 across the 10 of their papers we have counts for
4 papers · 1 filter
Learning Molecular Representation in a Cell
Gang Liu, Srijit Seal, John Arevalo +4
Predicting drug efficacy and safety in vivo requires information on biological responses (e.g., cell morphology and gene expression) to small molecule perturbations. However, curre…
MOTIVE: A Drug-Target Interaction Graph For Inductive Link Prediction
John Arevalo, Ellen Su, Anne E Carpenter +1
Drug-target interaction (DTI) prediction is crucial for identifying new therapeutics and detecting mechanisms of action. While structure-based methods accurately model physical int…
A Decade in a Systematic Review: The Evolution and Impact of Cell Painting
Srijit Seal, Maria-Anna Trapotsi, Ola Spjuth +5
High-content image-based assays have fueled significant discoveries in the life sciences in the past decade (2013-2023), including novel insights into disease etiology, mechanism o…
Cell Painting Gallery: an open resource for image-based profiling
Erin Weisbart, Ankur Kumar, John Arevalo +3
Image-based or morphological profiling is a rapidly expanding field wherein cells are "profiled" by extracting hundreds to thousands of unbiased, quantitative features from images…