9 citations · 23 across the 11 of their papers we have counts for
5 papers · 1 filter
Numerical and Lyapunov-Based Investigation of the Effect of Stenosis on Blood Transport Stability Using a Control-Theoretic PDE Model of Cardiovascular Flow
Shantanu Singh, Nikolaos Bekiaris-Liberis
We perform various numerical tests to study the effect of (boundary) stenosis on blood flow stability, employing a detailed and accurate, second-order finite-volume scheme for nume…
Learning Molecular Representation in a Cell
Gang Liu, Srijit Seal, John Arevalo +4
Predicting drug efficacy and safety in vivo requires information on biological responses (e.g., cell morphology and gene expression) to small molecule perturbations. However, curre…
MOTIVE: A Drug-Target Interaction Graph For Inductive Link Prediction
John Arevalo, Ellen Su, Anne E Carpenter +1
Drug-target interaction (DTI) prediction is crucial for identifying new therapeutics and detecting mechanisms of action. While structure-based methods accurately model physical int…
A Decade in a Systematic Review: The Evolution and Impact of Cell Painting
Srijit Seal, Maria-Anna Trapotsi, Ola Spjuth +5
High-content image-based assays have fueled significant discoveries in the life sciences in the past decade (2013-2023), including novel insights into disease etiology, mechanism o…
Understanding Biology in the Age of Artificial Intelligence
Elsa Lawrence, Adham El-Shazly, Srijit Seal +6
Modern life sciences research is increasingly relying on artificial intelligence approaches to model biological systems, primarily centered around the use of machine learning (ML)…