15 citations · 20 across the 12 of their papers we have counts for
12 papers · 1 filter
Circulating Lymphocytes Preservation in Lung Cancer Stereotactic Body Radiation Therapy with Ultra-Fast Proton Delivery Using Modularized Pin Ridge Filters
Duncan Bohannon, Ahmal Jawad Zafar, Sibo Tian +9
Purpose: Radiation-induced lymphopenia is an increasingly recognized toxicity in lung radiotherapy and has been linked to radiation exposure to circulating lymphocytes (CL). In int…
Optimizing Transmission FLASH Radiotherapy for Large-Field Post-Mastectomy Breast Treatment
Ahmal Jawad Zafar, Sunil William Dutta, Matthew Joseph Case +5
We investigated the effects of scanning speed, beam configuration, and dose-rate modeling on the FLASH effect in post-mastectomy proton transmission-beam (TB) planning and evaluate…
A Digital Twin Framework for Adaptive Treatment Planning in Radiotherapy
Chih-Wei Chang, Sri Sai Akkineni, Mingzhe Hu +7
The development of a digital twin (DT) framework for fast online adaptive proton therapy planning in prostate stereotactic body radiation therapy (SBRT) with dominant intraprostati…
Patient-Specific Deep Reinforcement Learning for Automatic Replanning in Head-and-Neck Cancer Proton Therapy
Malvern Madondo, Yuan Shao, Yingzi Liu +3
Anatomical changes during intensity-modulated proton therapy (IMPT) for head-and-neck cancer (HNC) can shift Bragg peaks, risking tumor underdosing and organ-at-risk overdosing. Tr…
Clinically Interpretable Survival Risk Stratification in Head and Neck Cancer Using Bayesian Networks and Markov Blankets
Keyur D. Shah, Ibrahim Chamseddine, Xiaohan Yuan +8
Purpose: To identify a clinically interpretable subset of survival-relevant features in HN cancer using Bayesian Network (BN) and evaluate its prognostic and causal utility. Method…
A Comparative Dosimetric Study of Proton and Photon Therapy in Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia
Keyur D. Shah, Chih-Wei Chang, Pretesh Patel +8
Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-inv…
Ultrafast Proton Delivery with Pin Ridge Filters (pRFs): A Novel Approach for Motion Management in Proton Therapy
Ahmal Jawad Zafar, Xiaofeng Yang, Yinan Wang +2
Active breath-hold techniques effectively mitigate respiratory motion but pose challenges for patients who are ineligible for the procedure. Conventional treatment planning relies…
An Adaptive Proton FLASH Therapy Using Modularized Pin Ridge Filter
Ahmal Jawad Zafar, Xiaofeng Yang, Zachary Diamond +4
In this paper, we proposed a method to optimize adaptive proton FLASH therapy (ADP FLASH) using modularized pin ridge filters (pRFs) by recycling module pins from the initial plan…
Stereotactic Arrhythmia Radioablation for Refractory Ventricular Tachycardia: A Narrative Review and Exploratory Pooled Analysis of Clinical Outcomes and Toxicity
Keyur D. Shah, Chih-Wei Chang, Sibo Tian +6
Purpose: Stereotactic arrhythmia radioablation (STAR) is a non-invasive salvage therapy for refractory ventricular tachycardia (VT), especially in patients ineligible for catheter…
Photon-Counting CT in Cancer Radiotherapy: Technological Advances and Clinical Benefits
Keyur D. Shah, Jun Zhou, Justin Roper +4
Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior sp…
Using Modularized Pin Ridge Filter in Proton FLASH Planning for Liver Stereotactic Ablative Body Radiotherapy
Chaoqiong Ma, Xiaofeng Yang, Yinan Wang +3
We previously developed a FLASH planning framework for streamlined pin-ridge-filter (pin-RF) design, demonstrating its feasibility for single-energy proton FLASH planning. In this…
Adaptive Proton Therapy Using CBCT-Guided Digital Twins
Chih-Wei Chang, Zhen Tian, Richard L. J. Qiu +8
This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a l…