activity
20232026
most citedModeling Complex Disease Trajectories using Deep Generative Models with Semi-Supervised Latent Processes

2 citations · 4 across the 11 of their papers we have counts for

collaborators

11 papers

cs.CV2026

Universal Boosts, Specific Suppressors: Sparse Autoencoder Steering of Medical Vision-Language Models

Farhad Nooralahzadeh, Benjamin Gundersen, Nicolas Deperrois +7

Medical vision-language models (VLMs) often hallucinate findings when generating chest X-ray reports: they fabricate findings that are not present in the image, miss important ones…

cs.LG2026

Repurposing Protein Language Models for Latent Flow-Based Fitness Optimization

Amaru Caceres Arroyo, Lea Bogensperger, Ahmed Allam +3

Protein fitness optimization is challenged by a vast combinatorial landscape where high-fitness variants are extremely sparse. Many current methods either underperform or require c…

cs.LG2025

A Variational Perspective on Generative Protein Fitness Optimization

Lea Bogensperger, Dominik Narnhofer, Ahmed Allam +2

The goal of protein fitness optimization is to discover new protein variants with enhanced fitness for a given use. The vast search space and the sparsely populated fitness landsca…

cs.LG2025

TAMER: A Test-Time Adaptive MoE-Driven Framework for EHR Representation Learning

Yinghao Zhu, Xiaochen Zheng, Ahmed Allam +1

We propose TAMER, a Test-time Adaptive MoE-driven framework for Electronic Health Record (EHR) Representation learning. TAMER introduces a framework where a Mixture-of-Experts (MoE…

cs.LG2024

Semi-Supervised Generative Models for Disease Trajectories: A Case Study on Systemic Sclerosis

Cécile Trottet, Manuel Schürch, Ahmed Allam +11

We propose a deep generative approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories, with a particular focus on Systemic Scle…

cs.LG2024

Clustering of Disease Trajectories with Explainable Machine Learning: A Case Study on Postoperative Delirium Phenotypes

Xiaochen Zheng, Manuel Schürch, Xingyu Chen +5

The identification of phenotypes within complex diseases or syndromes is a fundamental component of precision medicine, which aims to adapt healthcare to individual patient charact…

q-bio.GN2023★ 1 cited

Attention-based Multi-task Learning for Base Editor Outcome Prediction

Amina Mollaysa, Ahmed Allam, Michael Krauthammer

Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targ…

cs.LG2023

Attention-based Multi-task Learning for Base Editor Outcome Prediction

Amina Mollaysa, Ahmed Allam, Michael Krauthammer

Human genetic diseases often arise from point mutations, emphasizing the critical need for precise genome editing techniques. Among these, base editing stands out as it allows targ…

cs.LG2023★ 2 cited

Modeling Complex Disease Trajectories using Deep Generative Models with Semi-Supervised Latent Processes

Cécile Trottet, Manuel Schürch, Ahmed Allam +6

In this paper, we propose a deep generative time series approach using latent temporal processes for modeling and holistically analyzing complex disease trajectories. We aim to fin…

cs.LG2023

Two-Stage Aggregation with Dynamic Local Attention for Irregular Time Series

Xingyu Chen, Xiaochen Zheng, Amina Mollaysa +3

Irregular multivariate time series data is characterized by varying time intervals between consecutive observations of measured variables/signals (i.e., features) and varying sampl…

stat.ML2023★ 1 cited

Generating Personalized Insulin Treatments Strategies with Deep Conditional Generative Time Series Models

Manuel Schürch, Xiang Li, Ahmed Allam +4

We propose a novel framework that combines deep generative time series models with decision theory for generating personalized treatment strategies. It leverages historical patient…