6 citations · 10 across the 11 of their papers we have counts for
14 papers
Personalising Deformable Image Registration with Clinical Context and Deformation History for Adaptive Radiotherapy
Caiwen Jiang, Songlin Zhao, Yuzhen Ding +23
Adaptive radiotherapy must account for anatomical changes during treatment, but doing so depends on reliably mapping targets, organs at risk and dose across serial images. Existing…
Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Support
Qianxue Zhang, Yiming Ren, Shihuan Qin +18
In recent years, the advances of large language models and autonomous agents have revolutionized the healthcare field, facilitating diagnosis and improving treatment results. Howev…
AI in Proton Therapy Treatment Planning: A Review
Yuzhen Ding, Hongying Feng, Martin Bues +12
Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range unc…
An Automated Retrieval-Augmented Generation LLaMA-4 109B-based System for Evaluating Radiotherapy Treatment Plans
Junjie Cui, Peilong Wang, Jason Holmes +15
Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plan…
Causal Machine Learning Analysis of Empirical Relative Biological Effectiveness (RBE) for Mandible Osteoradionecrosis in Head and Neck Cancer Radiotherapy
Jingyuan Chen, Zhong Liu, Yunze Yang +8
Mandible Osteoradionecrosis (ORN) is one of the most severe adverse events (AEs) for head and neck (H&N) cancer radiotherapy. Previous retrospective investigations on real-world da…
Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy
Yuzhen Ding, Jason Holmes, Hongying Feng +13
Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anat…
Robust Optimization for Spot Scanning Proton Therapy based on Dose-Linear Energy Transfer (LET) Volume Constraints
Jingyuan Chen, Yunze Yang, Hongying Feng +8
Purpose: Historically, spot scanning proton therapy (SSPT) treatment planning utilizes dose volume constraints and linear-energy-transfer (LET) volume constraints separately to bal…
Fast Monte Carlo Dose Calculation in Proton Therapy
Jason Holmes, Hongying Feng, Lian Zhang +3
This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customizat…
Accurate Patient Alignment without Unnecessary Imaging Dose via Synthesizing Patient-specific 3D CT Images from 2D kV Images
Yuzhen Ding, Jason M. Holmes, Hongying Feng +8
In radiotherapy, 2D orthogonally projected kV images are used for patient alignment when 3D-on-board imaging(OBI) unavailable. But tumor visibility is constrained due to the projec…
Noisy probing dose facilitated dose prediction for pencil beam scanning proton therapy: physics enhances generalizability
Lian Zhang, Jason M. Holmes, Zhengliang Liu +11
Purpose: Prior AI-based dose prediction studies in photon and proton therapy often neglect underlying physics, limiting their generalizability to handle outlier clinical cases, esp…
Artificial Intelligence-Facilitated Online Adaptive Proton Therapy Using Pencil Beam Scanning Proton Therapy
Hongying Feng, Jie Shan, Carlos E. Vargas +10
We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool…
Study of linear energy transfer effect on rib fracture in breast patients receiving pencil-beam-scanning proton therapy
Yunze Yang, Kimberly R. Gergelis, Jiajian Shen +8
Purpose: To study the effect of proton linear energy transfer (LET) on rib fracture in breast cancer patients treated with pencil-beam scanning proton therapy (PBS) using a novel t…
Benchmarking a foundation LLM on its ability to re-label structure names in accordance with the AAPM TG-263 report
Jason Holmes, Lian Zhang, Yuzhen Ding +7
Purpose: To introduce the concept of using large language models (LLMs) to re-label structure names in accordance with the American Association of Physicists in Medicine (AAPM) Tas…
Modelling small block aperture in an in-house developed GPU-accelerated Monte Carlo-based dose engine for pencil beam scanning proton therapy
Hongying Feng, Jason M. Holmes, Sujay A. Vora +8
Purpose: To enhance an in-house graphic-processing-unit (GPU) accelerated virtual particle (VP)-based Monte Carlo (MC) proton dose engine (VPMC) to model aperture blocks in both do…