activity
20232026
most citedArtificial Intelligence-Facilitated Online Adaptive Proton Therapy Using Pencil Beam Scanning Proton Therapy

2 citations · 3 across the 6 of their papers we have counts for

collaborators

9 papers

eess.IV2026

Personalising Deformable Image Registration with Clinical Context and Deformation History for Adaptive Radiotherapy

Caiwen Jiang, Songlin Zhao, Yuzhen Ding +23

Adaptive radiotherapy must account for anatomical changes during treatment, but doing so depends on reliably mapping targets, organs at risk and dose across serial images. Existing…

cs.CV2026

A Multimodal Clinically Informed Coarse-to-Fine Framework for Longitudinal CT Registration in Proton Therapy

Caiwen Jiang, Yuzhen Ding, Mi Jia +14

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans…

cs.AI2025

An Automated Retrieval-Augmented Generation LLaMA-4 109B-based System for Evaluating Radiotherapy Treatment Plans

Junjie Cui, Peilong Wang, Jason Holmes +15

Purpose: To develop a retrieval-augmented generation (RAG) system powered by LLaMA-4 109B for automated, protocol-aware, and interpretable evaluation of radiotherapy treatment plan…

cs.AI2025★ 1 cited

RadOnc-GPT: An Autonomous LLM Agent for Real-Time Patient Outcomes Labeling at Scale

Jason Holmes, Yuexing Hao, Mariana Borras-Osorio +22

Manual labeling limits the scale, accuracy, and timeliness of patient outcomes research in radiation oncology. We present RadOnc-GPT, an autonomous large language model (LLM)-based…

physics.med-ph2025

Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy

Yuzhen Ding, Jason Holmes, Hongying Feng +13

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anat…

physics.med-ph2024

Robust Optimization for Spot Scanning Proton Therapy based on Dose-Linear Energy Transfer (LET) Volume Constraints

Jingyuan Chen, Yunze Yang, Hongying Feng +8

Purpose: Historically, spot scanning proton therapy (SSPT) treatment planning utilizes dose volume constraints and linear-energy-transfer (LET) volume constraints separately to bal…

physics.med-ph2023

Noisy probing dose facilitated dose prediction for pencil beam scanning proton therapy: physics enhances generalizability

Lian Zhang, Jason M. Holmes, Zhengliang Liu +11

Purpose: Prior AI-based dose prediction studies in photon and proton therapy often neglect underlying physics, limiting their generalizability to handle outlier clinical cases, esp…

physics.med-ph2023★ 2 cited

Artificial Intelligence-Facilitated Online Adaptive Proton Therapy Using Pencil Beam Scanning Proton Therapy

Hongying Feng, Jie Shan, Carlos E. Vargas +10

We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool…

physics.med-ph2023

Beam mask and sliding window-facilitated deep learning-based accurate and efficient dose prediction for pencil beam scanning proton therapy

Lian Zhang, Jason M. Holmes, Zhengliang Liu +12

Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent…