24 citations · 47 across the 14 of their papers we have counts for
16 papers
Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Support
Qianxue Zhang, Yiming Ren, Shihuan Qin +18
In recent years, the advances of large language models and autonomous agents have revolutionized the healthcare field, facilitating diagnosis and improving treatment results. Howev…
AI in Proton Therapy Treatment Planning: A Review
Yuzhen Ding, Hongying Feng, Martin Bues +12
Purpose: Proton therapy provides superior dose conformity compared to photon therapy, but its treatment planning is challenged by sensitivity to anatomical changes, setup/range unc…
Diffusion Transformer-based Universal Dose Denoising for Pencil Beam Scanning Proton Therapy
Yuzhen Ding, Jason Holmes, Hongying Feng +13
Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anat…
Critical review of patient outcome study in head and neck cancer radiotherapy
Jingyuan Chen, Yunze Yang, Chenbin Liu +8
Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities cause…
Enabling Clinical Use of Linear Energy Transfer in Proton Therapy for Head and Neck Cancer -- A Review of Implications for Treatment Planning and Adverse Events Study
Jingyuan Chen, Yunze Yang, Hongying Feng +12
Proton therapy offers significant advantages due to its unique physical and biological properties, particularly the Bragg peak, enabling precise dose delivery to tumors while spari…
Robust Optimization for Spot Scanning Proton Therapy based on Dose-Linear Energy Transfer (LET) Volume Constraints
Jingyuan Chen, Yunze Yang, Hongying Feng +8
Purpose: Historically, spot scanning proton therapy (SSPT) treatment planning utilizes dose volume constraints and linear-energy-transfer (LET) volume constraints separately to bal…
Fast Monte Carlo Dose Calculation in Proton Therapy
Jason Holmes, Hongying Feng, Lian Zhang +3
This article examines the critical role of fast Monte Carlo dose calculations in advancing proton therapy techniques, particularly in the context of increasing treatment customizat…
Accurate Patient Alignment without Unnecessary Imaging Dose via Synthesizing Patient-specific 3D CT Images from 2D kV Images
Yuzhen Ding, Jason M. Holmes, Hongying Feng +8
In radiotherapy, 2D orthogonally projected kV images are used for patient alignment when 3D-on-board imaging(OBI) unavailable. But tumor visibility is constrained due to the projec…
Proton Pencil-Beam Scanning Stereotactic Body Radiation Therapy and Hypofractionated Radiation Therapy for Thoracic Malignancies: Patterns of Practice Survey and Recommendations for Future Development from NRG Oncology and PTCOG
Wei Liu, Hongying Feng, Paige A. Taylor +13
Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combinin…
The Radiation Oncology NLP Database
Zhengliang Liu, Jason Holmes, Wenxiong Liao +12
We present the Radiation Oncology NLP Database (ROND), the first dedicated Natural Language Processing (NLP) dataset for radiation oncology, an important medical specialty that has…
Noisy probing dose facilitated dose prediction for pencil beam scanning proton therapy: physics enhances generalizability
Lian Zhang, Jason M. Holmes, Zhengliang Liu +11
Purpose: Prior AI-based dose prediction studies in photon and proton therapy often neglect underlying physics, limiting their generalizability to handle outlier clinical cases, esp…
Artificial Intelligence-Facilitated Online Adaptive Proton Therapy Using Pencil Beam Scanning Proton Therapy
Hongying Feng, Jie Shan, Carlos E. Vargas +10
We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool…
Benchmarking a foundation LLM on its ability to re-label structure names in accordance with the AAPM TG-263 report
Jason Holmes, Lian Zhang, Yuzhen Ding +7
Purpose: To introduce the concept of using large language models (LLMs) to re-label structure names in accordance with the American Association of Physicists in Medicine (AAPM) Tas…
Modelling small block aperture in an in-house developed GPU-accelerated Monte Carlo-based dose engine for pencil beam scanning proton therapy
Hongying Feng, Jason M. Holmes, Sujay A. Vora +8
Purpose: To enhance an in-house graphic-processing-unit (GPU) accelerated virtual particle (VP)-based Monte Carlo (MC) proton dose engine (VPMC) to model aperture blocks in both do…
Segment Anything Model (SAM) for Radiation Oncology
Lian Zhang, Zhengliang Liu, Lu Zhang +10
In this study, we evaluate the performance of the Segment Anything Model (SAM) in clinical radiotherapy. Our results indicate that SAM's 'segment anything' mode can achieve clinica…
Deep-Learning-based Fast and Accurate 3D CT Deformable Image Registration in Lung Cancer
Yuzhen Ding, Hongying Feng, Yunze Yang +9
Purpose: In some proton therapy facilities, patient alignment relies on two 2D orthogonal kV images, taken at fixed, oblique angles, as no 3D on-the-bed imaging is available. The v…