6 citations · 13 across the 12 of their papers we have counts for
8 papers · 1 filter
ProteinOPD: Towards Effective and Efficient Preference Alignment for Protein Design
Yulin Zhang, He Cao, Zihao Jiang +6
Designing proteins with desired functions or properties represents a core goal in synthetic biology and drug discovery. Recent advances in protein language models (PLMs) have enabl…
RAPTOR: Ridge-Adaptive Logistic Probes
Ziqi Gao, Yaotian Zhu, Qingcheng Zeng +4
Probing studies what information is encoded in a frozen LLM's layer representations by training a lightweight predictor on top of them. Beyond analysis, probes are often used opera…
Revisiting LoRA through the Lens of Parameter Redundancy: Spectral Encoding Helps
Jiashun Cheng, Aochuan Chen, Nuo Chen +4
Low-Rank Adaptation (LoRA) has emerged as a prominent technique for fine-tuning large foundation models. Despite its successes, the substantial parameter redundancy, which limits t…
Mini-Game Lifetime Value Prediction in WeChat
Aochuan Chen, Yifan Niu, Ziqi Gao +5
The LifeTime Value (LTV) prediction, which endeavors to forecast the cumulative purchase contribution of a user to a particular item, remains a vital challenge that advertisers are…
InversionGNN: A Dual Path Network for Multi-Property Molecular Optimization
Yifan Niu, Ziqi Gao, Tingyang Xu +5
Exploring chemical space to find novel molecules that simultaneously satisfy multiple properties is crucial in drug discovery. However, existing methods often struggle with trading…
Molecule Generation for Target Protein Binding with Hierarchical Consistency Diffusion Model
Guanlue Li, Chenran Jiang, Ziqi Gao +5
Effective generation of molecular structures, or new chemical entities, that bind to target proteins is crucial for lead identification and optimization in drug discovery. Despite…
Parameter-Efficient Fine-Tuning via Circular Convolution
Aochuan Chen, Jiashun Cheng, Zijing Liu +4
Low-Rank Adaptation (LoRA) has gained popularity for fine-tuning large foundation models, leveraging low-rank matrices and to represent weight changes (i.…
Parameter-Efficient Fine-Tuning with Discrete Fourier Transform
Ziqi Gao, Qichao Wang, Aochuan Chen +4
Low-rank adaptation~(LoRA) has recently gained much interest in fine-tuning foundation models. It effectively reduces the number of trainable parameters by incorporating low-rank m…