most citedThe Canadian VirusSeq Data Portal & Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology

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q-bio.PE2014

Reconstructing subclonal composition and evolution from whole genome sequencing of tumors

Amit G. Deshwar, Shankar Vembu, Christina K. Yung +3

Tumors often contain multiple subpopulations of cancerous cells defined by distinct somatic mutations. We describe a new method, PhyloWGS, that can be applied to WGS data from one…