3 papers
q-bio.BM2024
Deep learning assisted SERS detection of prolines and hydroxylated prolines using nitrilotriacetic acid functionalized gold nanopillars
Yuan Zhang, Kuo Zhan, Peilin Xin +5
Proline (Pro) is one kind of proteinogenic amino acid and an important signaling molecule in the process of metabolism. Hydroxyproline (Hyp) is a product on Pro oxygen sensing post…
physics.app-ph2024
A novel particle-in-well technology for single-molecule sequencing by surface-enhanced Raman spectroscopy
Eva Bozo, Pei-Lin Xin, Yingqi Zhao +5
Single-molecule surface-enhanced Raman spectroscopy based on a particle trapped in a plasmonic nanopores provides a unique method for continued and controlled detection of peptide…
q-bio.QM2024
SAPNet: a deep learning model for identification of single-molecule peptide post-translational modifications with surface enhanced Raman spectroscopy
Mulusew W. Yaltaye, Yingqi Zhao, Eva Bozo +4
Nanopore resistive pulse sensors are emerging technologies for single-molecule protein sequencing. But they can hardly detect small post-translational modifications (PTMs) such as…