4 papers
Scaling effects in the Penna ageing model
A. Laszkiewicz, S. Cebrat, D. Stauffer
We have analysed the possibility of scaling the sexual Penna ageing model. Assuming that the number of genes expressed before the reproduction age grows linearly with the genome si…
Does telomere elongation in cloned organisms lead to a longer lifespan if cancer is considered ?
M. Masa, S. Cebrat, D. Stauffer
... By additionally considering a two-mutation model for carcinogenesis and indefinite proliferation by the activation of telomerase, we demonstrate that the risk of dying doe to c…
Altruism and Antagonistic Pleiotropy in Penna Ageing Model
Stanislaw Cebrat, Dietrich Stauffer
The Penna ageing model is based on mutation accumulation theory. We show that it also allows for self-organization of antagonistic pleiotropy which helps at young age at the expens…
Genetic Paralog Analysis and Simulations
Stanislaw Cebrat, Jan P. Radomski, Dietrich Stauffer
Using Monte Carlo methods, we simulated the effects of bias in generation and elimination of paralogs on the size distribution of paralog groups. It was found that the function des…