3 papers
q-bio.NC2025
Mixed genetic background better recapitulates developmental and psychiatric phenotypes and heterogeneity than inbred C57BL/6J mice
Ana Dudas, Ana Novak, Caroline Gora +4
Preclinical models of neurodevelopmental and psychiatric conditions often rely on inbred mouse strains like C57BL/6J (B6), which exhibit limited genetic and behavioral variability.…
q-bio.NC2025
The insertion of Neomycin cassette impairs maternal and social behaviors in Arc/Arg3.1 knock-out mice
Ana Dudas, Emilia Caire, Abdurahman Hassan a Kuku +14
The Neomycin resistance cassette (Neo+) is commonly inserted in the genome of mice to generate knock-out (KO) models. The effect of gene deletion on social behaviors in mice is con…
q-bio.NC2024
Effect of the social environment on olfaction and social skills in WT and mouse model of autism
Caroline Gora, Ana Dudas, Lucas Court +13
Autism spectrum disorders are complex, polygenic and heterogenous neurodevelopmental conditions, imposing a substantial economic burden. Genetics are influenced by the environment,…