3 papers
physics.bio-ph2024
Target search on networks-within-networks with applications to protein-DNA interactions
Lucas Hedström, Seong-Gyu Yang, Ludvig Lizana
We present a novel framework for understanding node target search in systems organized as hierarchical networks-within-networks. Our work generalizes traditional search models on c…
cond-mat.soft2024
Considerations on the relaxation time in shear-driven jamming
Lucas Hedström, Peter Olsson
We study the jamming transition in a model of elastic particles under shear at zero temperature, with a focus on the relaxation time . This relaxation time is from two-step si…
q-bio.MN2024
A general mechanism for enhancer-insulator pairing reveals heterogeneous dynamics in long-distant 3D gene regulation
Lucas Hedström, Ralf Metzler, Ludvig Lizana
Cells regulate fates and complex body plans using spatiotemporal signaling cascades that alter gene expression. Enhancers, short DNA sequences (50-150 base pairs), help coordinate…