2 papers
physics.bio-ph2024
Exploring the Thermostability of CRISPR Cas12b using Molecular Dynamics Simulations
Yinhao Jia, Katelynn Horvath, Santosh R. Rananaware +2
CRISPR (clustered regularly interspaced short palindromic repeat)- based diagnostics are at the forefront of rapid detection platforms of infectious diseases. The integration of re…
physics.bio-ph2024
Insights into Protein Unfolding under pH, Temperature, and Shear using Molecular Dynamics Simulations
Yinhao Jia, Clare Cocker, Janani Sampath
Protein biologics hold immense potential in therapeutic applications, but their ephemeral nature has hindered their widespread application. The effects of different stressors on pr…