8 citations · 18 across the 13 of their papers we have counts for
13 papers
Cyclooxygenase inhibition in ischemic brain injury
Eduardo Candelario-Jalil, Bernd L. Fiebich
Neuroinflammation is one of the key pathological events involved in the progression of brain damage caused by cerebral ischemia. Metabolism of arachidonic acid through cyclooxygena…
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat
Eduardo Candelario-Jalil, Saeid Taheri, Yi Yang +5
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor…
Selective vulnerability to kainate-induced oxidative damage in different rat brain regions
E. Candelario-Jalil, S. M. Al-Dalain, R. Castillo +2
Some markers of oxidative injury were measured in different rat brain areas (hippocampus, cerebral cortex, striatum, hypothalamus, amygdala/piriform cortex and cerebellum) after th…
Nimesulide limits kainate-induced oxidative damage in the rat hippocampus
E. Candelario-Jalil, H. H. Ajamieh, S. Sam +2
Kainate induces a marked expression of cyclooxygenase-2 after its systemic administration. Because cyclooxygenase-2 activity is associated to the production of reactive oxygen spec…
Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats
A. Gonzalez-Falcon, E. Candelario-Jalil, M. Garcia-Cabrera +1
Recent experimental evidences indicate that pyruvate, the final metabolite of glycolysis, has a remarkable protective effect against different types of brain injury. The purpose of…
The highly selective cyclooxygenase-2 inhibitor DFU is neuroprotective when given several hours after transient cerebral ischemia in gerbils
E. Candelario-Jalil, D. Alvarez, J. M. Castaneda +4
Several studies suggest that cyclooxygenase-2 contributes to the delayed progression of ischemic brain damage. In this study we examined whether the highly selective cyclooxygenase…