1 citations · 1 across the 3 of their papers we have counts for
3 papers
q-bio.BM2005
A folding inhibitor of the HIV-1 Protease
R. A. Broglia, D. Provasi, F. Vasile +3
Being the HIV-1 Protease (HIV-1-PR) an essential enzyme in the viral life cycle, its inhibition can control AIDS. The folding of single domain proteins, like each of the monomers f…
q-bio.BM2005★ 1 cited
Design of HIV-1-PR inhibitors which do not create resistance: blocking the folding of single monomers
R. A. Broglia, G. Tiana, L. Sutto +2
One of the main problems of drug design is that of optimizing the drug--target interaction. In the case in which the target is a viral protein displaying a high mutation rate, a se…
q-bio.BM2004
Design of a folding inhibitor of the HIV-1 Protease
R. A. Broglia, G. Tiana, D. Provasi +4
Being HIV-1-PR an essential enzyme in the viral life cycle, its inhibition can control AIDS. Because the folding of single domain proteins, like HIV-1-PR is controlled by local ele…