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stat.ME2025
Covariate-adjusted Group Sequential Comparisons of Restricted Mean Survival Times
Peter Zhang, Brent Logan, Michael Martens
The restricted mean survival time (RMST) is the mean survival time in the study population followed up to a specific time point, and is simply the area under the survival curve up…
stat.ME2024
Covariate-adjusted Group Sequential Comparisons of Survival Probabilities
Peter Zhang, Brent Logan, Michael Martens
In confirmatory clinical trials, survival outcomes are frequently studied and interim analyses for efficacy and/or futility are often desirable. Methods such as the log rank test a…