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physics.bio-ph2010
Role of Loading Device on Single-Molecule Mechanical Manipulation of Free Energy Landscape
Gwonchan Yoon, Sungsoo Na, Kilho Eom
Single-molecule mechanical manipulation has enabled the quantitative understanding of the kinetics of bond ruptures as well as protein unfolding mechanism. Single-molecule experime…
physics.bio-ph2004★ 36 cited
Theoretical studies of the kinetics of mechanical unfolding of cross-linked polymer chains and their implications for single molecule pulling experiments
Kilho Eom, Dmitrii E Makarov, Gregory J. Rodin
We have used kinetic Monte Carlo simulations to study the kinetics of unfolding of cross-linked polymer chains under mechanical loading. As the ends of a chain are pulled apart, th…