activity
20062015
most citedNonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches

54 citations · 81 across the 4 of their papers we have counts for

collaborators

4 papers

q-bio.QM2015★ 10 cited

A pharmacokinetic -- viral kinetic model describes the effect of alisporivir monotherapy or in combination with peg-IFN on 2 hepatitis C virologic response

Thi Huyen Tram Nguyen, France Mentré, Micha Levi +2

Alisporivir is a cyclophilin inhibitor with demonstrated in vitro and in vivo activity against hepatitis C 11 virus (HCV). We estimated antiviral effectiveness of alisporivir alone…

q-bio.QM2015★ 54 cited

Nonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches

Soléne Desmée, France Mentré, Christine Veyrat-Follet +1

In metastatic castration-resistant prostate cancer (mCRPC) clinical trials, the assessment of treatment efficacy essentially relies on the time-to-death and the kinetics of prostat…

stat.ME2008★ 1 cited

Estimating a difference between Kullback-Leibler risks by a normalized difference of AIC

D. Commenges, A. Sayyareh, L. Letenneur +2

AIC is commonly used for model selection but the precise value of AIC has no direct interpretation. We are interested in quantifying a difference of risks between two models. This…

math.ST2006★ 16 cited

A Newton-Like Algorithm for Likelihood Maximization: The Robust-Variance Scoring Algorithm

Daniel Commenges, Helene Jacqmin-Gadda, Cecile Proust +1

This article studies a Newton-like method already used by several authors but which has not been thouroughly studied yet. We call it the robust-variance scoring (RVS) algorithm bec…