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Network modelling of topological domains using Hi-C data
Y. X. Rachel Wang, Purnamrita Sarkar, Oana Ursu +2
Chromosome conformation capture experiments such as Hi-C are used to map the three-dimensional spatial organization of genomes. One specific feature of the 3D organization is known…
A model for sequential evolution of ligands by exponential enrichment (SELEX) data
Juli Atherton, Nathan Boley, Ben Brown +5
A Systematic Evolution of Ligands by EXponential enrichment (SELEX) experiment begins in round one with a random pool of oligonucleotides in equilibrium solution with a target. Ove…
Measuring reproducibility of high-throughput experiments
Qunhua Li, James B. Brown, Haiyan Huang +1
Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings…
Subsampling Methods for genomic inference
Peter J. Bickel, Nathan Boley, James B. Brown +2
Large-scale statistical analysis of data sets associated with genome sequences plays an important role in modern biology. A key component of such statistical analyses is the comput…
Leo Breiman: An important intellectual and personal force in statistics, my life and that of many others
Peter J. Bickel
I first met Leo Breiman in 1979 at the beginning of his third career, Professor of Statistics at Berkeley. He obtained his PhD with Loéve at Berkeley in 1957. His first career was…
Discussion of: Treelets--An adaptive multi-scale basis for sparse unordered data
Peter J. Bickel, Ya'acov Ritov
Discussion of "Treelets--An adaptive multi-scale basis for sparse unordered data" [arXiv:0707.0481]