6 papers
On Focusing Statistical Power for Searches and Measurements in Particle Physics
James Carzon, Aishik Ghosh, Rafael Izbicki +3
Particle physics experiments rely on the (generalised) likelihood ratio test (LRT) for searches and measurements, which consist of composite hypothesis tests. However, this test is…
On the Codesign of Scientific Experiments and Industrial Systems
Tommaso Dorigo, Pietro Vischia, Shahzaib Abbas +84
The optimization of large experiments in fundamental science, such as detectors for subnuclear physics at particle colliders, shares with the optimization of complex systems for in…
Trustworthy scientific inference with generative models
James Carzon, Luca Masserano, Joshua D. Ingram +7
Generative artificial intelligence (AI) excels at producing complex data structures (text, images, videos) by learning patterns from training examples. Across scientific discipline…
Toward the End-To-End Optimization of the SWGO Array Layout
Tommaso Dorigo, Max Aehle, Cornelia Arcaro +13
In this document we consider the problem of finding the optimal layout for the array of water Cherenkov detectors proposed by the SWGO collaboration to study very-high-energy gamma…
On the Utility Function of Experiments in Fundamental Science
Tommaso Dorigo, Michele Doro, Max Aehle +7
The majority of experiments in fundamental science today are designed to be multi-purpose: their aim is not simply to measure a single physical quantity or process, but rather to e…
Likelihood-Free Frequentist Inference: Bridging Classical Statistics and Machine Learning for Reliable Simulator-Based Inference
Niccolò Dalmasso, Luca Masserano, David Zhao +2
Many areas of science rely on simulators that implicitly encode intractable likelihood functions of complex systems. Classical statistical methods are poorly suited for these so-ca…