2 papers
stat.ME2024
Chauhan Weighted Trajectory Analysis of combined efficacy and safety outcomes for risk-benefit analysis
Utkarsh Chauhan, Daylen Mackey, John R Mackey
Analyzing and effectively communicating the efficacy and toxicity of treatment is the basis of risk benefit analysis (RBA). More efficient and objective tools are needed. We apply…
stat.ME2024
Chauhan Weighted Trajectory Analysis reduces sample size requirements and expedites time-to-efficacy signals in advanced cancer clinical trials
Utkarsh Chauhan, Daylen Mackey, John R. Mackey
As Kaplan-Meier (KM) analysis is limited to single unidirectional endpoints, most advanced cancer randomized clinical trials (RCTs) are powered for either progression free survival…