286 citations · 1.9k across the 27 of their papers we have counts for
10 papers · 1 filter
A generalized theory of semiflexible polymers
Paul A. Wiggins, Philip C. Nelson
DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experime…
Exact theory of kinkable elastic polymers
Paul A. Wiggins, Rob Phillips, Philip C. Nelson
The importance of nonlinearities in material constitutive relations has long been appreciated in the continuum mechanics of macroscopic rods. Although the moment (torque) response…
Transport of Torsional Stress in DNA
Philip Nelson
It is well known that transcription can induce torsional stress in DNA, affecting the activity of nearby genes or even inducing structural transitions in the DNA duplex. It has lon…
Entropic Elasticity of Twist-Storing Polymers
J. David Moroz, Philip Nelson
We investigate the statistical mechanics of a torsionally constrained polymer. The polymer is modeled as a fluctuating rod with bend stiffness A kT and twist stiffness C kT. In suc…
Sequence Effects on DNA Entropic Elasticity
Philip Nelson
DNA stretching experiments are usually interpreted using the worm-like chain model; the persistence length A appearing in the model is then interpreted as the elastic stiffness of…
Hard Spheres in Vesicles: Curvature-Induced Forces and Particle-Induced Curvature
A. D. Dinsmore, D. T. Wong, Philip Nelson +1
We explore the interplay of membrane curvature and nonspecific binding due to excluded-volume effects among colloidal particles inside lipid bilayer vesicles. We trapped submicron…