3 citations · 6 across the 17 of their papers we have counts for
17 papers · 1 filter
Open diffusion MRI and connectivity data for epilepsy and surgery: The IDEAS II release
Peter N. Taylor, Gerard Hall, Jonathan Horsley +7
Epileptic seizures are generated in cerebral networks that propagate ictal and interictal activity. The structure of cerebral networks underpinning epileptic activity can be inferr…
Seizure duration is associated with multiple timescales in interictal iEEG band power
Mariella Panagiotopoulou, Gabrielle M. Schroeder, Jess Blickwedel +12
Background Seizure severity can change from one seizure to the next within individual people with epilepsy. It is unclear if and how seizure severity is modulated over longer times…
Dual mechanism of Anti-Seizure Medications in controlling seizure activity
Guillermo M. Besne, Emmanuel Molefi, Sarah J. Gascoigne +12
Background: Anti-seizure medications (ASMs) can reduce seizure duration, but their precise modes of action are unclear. Specifically, it is unknown whether ASMs shorten seizures by…
Combined impact of grey and superficial white matter abnormalities: implications for epilepsy surgery
Csaba Kozma, Jonathan Horsley, Gerard Hall +9
Drug-resistant focal epilepsy is associated with abnormalities in the brain in both grey matter (GM) and superficial white matter (SWM). However, it is unknown if both types of abn…
Automated generation of epilepsy surgery resection masks; The RAMPS pipeline
Callum Simpson, Gerard Hall, John S. Duncan +2
MRI-based delineation of brain tissue removed by epilepsy surgery can be challenging due to post-operative brain shift. In consequence, most studies use manual approaches which are…
Seizure freedom after surgical resection of diffusion-weighted MRI abnormalities
Jonathan Horsley, Gerard Hall, Callum Simpson +10
Importance: Many individuals with drug-resistant epilepsy continue to have seizures after resective surgery. Accurate identification of focal brain abnormalities is essential for s…
Anti-seizure medication load is not correlated with early termination of seizure spread
Nathan Evans, Sarah J. Gascoigne, Guillermo M. Besne +11
Objective: Anti-seizure medications (ASMs) are the mainstay of treatment for epilepsy, yet their effect on seizure spread is not fully understood. Higher ASM doses have been associ…
Status epilepticus and thinning of the entorhinal cortex
Jonathan Horsley, Yujiang Wang, Callum Simpson +6
Status epilepticus (SE) carries risks of morbidity and mortality. Experimental studies have implicated the entorhinal cortex in prolonged seizures; however, studies in large human…
The Imaging Database for Epilepsy And Surgery (IDEAS)
Peter N. Taylor, Yujiang Wang, Callum Simpson +12
Magnetic resonance imaging (MRI) is a crucial tool to identify brain abnormalities in a wide range of neurological disorders. In focal epilepsy MRI is used to identify structural c…
Brain Morphology Normative modelling platform for abnormality and Centile estimation: Brain MoNoCle
Bethany Little, Nida Alyas, Alexander Surtees +7
Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller…
Anti-seizure medication tapering correlates with daytime delta band power reduction in the cortex
Guillermo M. Besne, Nathan Evans, Mariella Panagiotopoulou +11
Anti-seizure medications (ASMs) are the primary treatment for epilepsy, yet medication tapering effects have not been investigated in a dose, region, and time-dependent manner, des…
Alpha rhythm slowing in temporal epilepsy across Scalp EEG and MEG
Vytene Janiukstyte, Csaba Kozma, Thomas W. Owen +8
EEG slowing is reported in various neurological disorders including Alzheimer's, Parkinson's and Epilepsy. Here, we investigate alpha rhythm slowing in individuals with refractory…
Multi-centre normative brain mapping of intracranial EEG lifespan patterns in the human brain
Heather Woodhouse, Gerard Hall, Callum Simpson +18
Background: Understanding healthy human brain function is crucial to identify and map pathological tissue within it. Whilst previous studies have mapped intracranial EEG (icEEG) fr…
Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes
Sarah J. Gascoigne, Nathan Evans, Gerard Hall +16
Delineation of seizure onset regions from EEG is important for effective surgical workup. However, it is unknown if their complete resection is required for seizure freedom, or in…
Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo
Christopher Thornton, Mariella Panagiotopoulou, Fahmida A Chowdhury +10
Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expressio…
Normative brain mapping using scalp EEG and potential clinical application
Vytene Janiukstyte, Thomas W Owen, Umair J Chaudhary +6
A normative electrographic activity map could be a powerful resource to understand normal brain function and identify abnormal activity. Here, we present a normative brain map usin…
Temporal stability of intracranial EEG abnormality maps for localising epileptogenic tissue
Yujiang Wang, Gabrielle M Schroeder, Jonathan J Horsley +8
Objective: Identifying abnormalities in interictal intracranial EEG, by comparing patient data to a normative map, has shown promise for the localisation of epileptogenic tissue an…