1 citations · 1 across the 8 of their papers we have counts for
8 papers
Habitual lifestyle timing explains circadian timing, but daily lifestyle changes do not, in free-living humans across 2000 days
Billy C. Smith, Zeel Pansara, Rosanne H. Timmerman +11
Background: Both between- and within-subject variations in circadian timing matter for health. If lifestyle changes could be used to regulate circadian timing, they would offer acc…
Multimodal Modeling of Ultradian Rhythms Using the Hankel Alternative View of Koopman (HAVOK) Analysis
Emmanuel Molefi, Billy C. Smith, Christopher Thornton +2
Ultradian rhythms - quasi-rhythmic fluctuations in behavior and physiology with periods shorter than 24 hours - are observed across various organisms, including humans. Despite the…
Dual mechanism of Anti-Seizure Medications in controlling seizure activity
Guillermo M. Besne, Emmanuel Molefi, Sarah J. Gascoigne +12
Background: Anti-seizure medications (ASMs) can reduce seizure duration, but their precise modes of action are unclear. Specifically, it is unknown whether ASMs shorten seizures by…
More variable circadian rhythms in epilepsy captured by long-term heart rate recordings from wearable sensors
Billy C. Smith, Christopher Thornton, Rachel E. Stirling +7
Objective: The circadian rhythm synchronizes physiological and behavioural patterns with the 24-hour light-dark cycle. Disruption to the circadian rhythm is linked to various healt…
Comparing Methodological Variations in Seizure Onset Localisation Algorithms using intracranial EEG
Sarah J. Gascoigne, Manel Vila-Vidal, Nathan Evans +9
During clinical treatment for epilepsy, the area of the brain thought to be responsible for pathological activity is identified. This identification is typically performed through…
Unsupervised Machine Learning Identifies Latent Ultradian States in Multi-Modal Wearable Sensor Signals
Christopher Thornton, Billy C. Smith, Guillermo M. Besne +2
Wearable sensors such as smartwatches have become ubiquitous in recent years, allowing the easy and continual measurement of physiological parameters such as heart rate, physical a…
Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes
Sarah J. Gascoigne, Nathan Evans, Gerard Hall +16
Delineation of seizure onset regions from EEG is important for effective surgical workup. However, it is unknown if their complete resection is required for seizure freedom, or in…
Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo
Christopher Thornton, Mariella Panagiotopoulou, Fahmida A Chowdhury +10
Chronobiological rhythms, such as the circadian rhythm, have long been linked to neurological disorders, but it is currently unknown how pathological processes affect the expressio…