1 citations · 1 across the 7 of their papers we have counts for
7 papers
Dual mechanism of Anti-Seizure Medications in controlling seizure activity
Guillermo M. Besne, Emmanuel Molefi, Sarah J. Gascoigne +12
Background: Anti-seizure medications (ASMs) can reduce seizure duration, but their precise modes of action are unclear. Specifically, it is unknown whether ASMs shorten seizures by…
From Bedside to Desktop: A Data Protocol for Normative Intracranial EEG and Abnormality Mapping
Heather Woodhouse, Sarah J. Gascoigne, Gerard Hall +5
Normative mapping is a framework used to map population-level features of health-related variables. It is widely used in neuroscience research, but the literature lacks established…
More variable circadian rhythms in epilepsy captured by long-term heart rate recordings from wearable sensors
Billy C. Smith, Christopher Thornton, Rachel E. Stirling +7
Objective: The circadian rhythm synchronizes physiological and behavioural patterns with the 24-hour light-dark cycle. Disruption to the circadian rhythm is linked to various healt…
Comparing Methodological Variations in Seizure Onset Localisation Algorithms using intracranial EEG
Sarah J. Gascoigne, Manel Vila-Vidal, Nathan Evans +9
During clinical treatment for epilepsy, the area of the brain thought to be responsible for pathological activity is identified. This identification is typically performed through…
Anti-seizure medication load is not correlated with early termination of seizure spread
Nathan Evans, Sarah J. Gascoigne, Guillermo M. Besne +11
Objective: Anti-seizure medications (ASMs) are the mainstay of treatment for epilepsy, yet their effect on seizure spread is not fully understood. Higher ASM doses have been associ…
Anti-seizure medication tapering correlates with daytime delta band power reduction in the cortex
Guillermo M. Besne, Nathan Evans, Mariella Panagiotopoulou +11
Anti-seizure medications (ASMs) are the primary treatment for epilepsy, yet medication tapering effects have not been investigated in a dose, region, and time-dependent manner, des…
Incomplete resection of the icEEG seizure onset zone is not associated with post-surgical outcomes
Sarah J. Gascoigne, Nathan Evans, Gerard Hall +16
Delineation of seizure onset regions from EEG is important for effective surgical workup. However, it is unknown if their complete resection is required for seizure freedom, or in…