34 citations · 45 across the 5 of their papers we have counts for
5 papers
Centered Isotonic Regression: Point and Interval Estimation for Dose-Response Studies
Assaf P. Oron, Nancy Flournoy
Univariate isotonic regression (IR) has been used for nonparametric estimation in dose-response and dose-finding studies. One undesirable property of IR is the prevalence of piecew…
Small-Sample Behavior of Novel Phase I Cancer Trial Designs
Assaf P. Oron, Peter D. Hoff
Novel dose-finding designs, using estimation to assign the best estimated maximum- tolerated-dose (MTD) at each point in the experiment, most commonly via Bayesian techniques, have…
Is There Statistical Evidence that the Oregon Payday-Loan Rate Cap Hurts Consumers?
Assaf P. Oron
1. A recent unpublished manuscript whose conclusions were widely circulated in the electronic media (Zinman, 2009) claimed that Oregon 2007 payday loan (PL) rate-limiting regulatio…
Convergence of Nonparametric Long-Memory Phase I Designs
Assaf P. Oron, David Azriel, Peter D. Hoff
We examine nonparametric dose-finding designs that use toxicity estimates based on all available data at each dose allocation decision. We prove that one such design family, called…
Up-and-Down and the Percentile-Finding Problem
Assaf P. Oron
Up-and-Down (U&D) is a popular sequential design for estimating threshold percentiles in binary experiments. However, U&D application practices have stagnated, and significant gaps…