activity
20052024
most citedCapturing the essence of folding and functions of biomolecules using Coarse-Grained Models

264 citations · 2.9k across the 73 of their papers we have counts for

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Showing physics.bio-phShow all

11 papers · 1 filter

physics.bio-ph2021★ 1 cited

Thermodynamic optimality of glycolytic oscillations

Pureun Kim, Changbong Hyeon

Temporal order in living matters reflects the self-organizing nature of dynamical processes driven out of thermodynamic equilibrium. Because of functional reason, the period of a b…

physics.bio-ph2021★ 26 cited

Thermodynamic uncertainty relation to assess biological processes

Yonghyun Song, Changbong Hyeon

We review the trade-offs between speed, fluctuations, and thermodynamic cost involved with biological processes in nonequilibrium states, and discuss how optimal these processes ar…

physics.bio-ph2020★ 28 cited

Thermodynamic cost, speed, fluctuations, and error reduction of biological copy machines

Yonghyun Song, Changbong Hyeon

Due to large fluctuations in cellular environments, transfer of information in biological processes without regulation is inherently error-prone. The mechanistic details of error-r…

physics.bio-ph2019★ 91 cited

Theoretical Perspectives on Biological Machines

Mauro L. Mugnai, Changbong Hyeon, Michael Hinczewski +1

Many biological functions are executed by molecular machines, which consume energy and convert it into mechanical work. Biological machines have evolved to transport cargo, facilit…

physics.bio-ph2017★ 115 cited

Energetic costs, precision, and efficiency of a biological motor in cargo transport

Wonseok Hwang, Changbong Hyeon

Molecular motors play pivotal roles in organizing the interior of cells. A motor efficient in cargo transport would move along cytoskeletal filaments with a high speed and a minima…

physics.bio-ph2016

Ripping RNA by Force using Gaussian Network Models

Changbong Hyeon, D. Thirumalai

Using force as a probe to map the folding landscapes of RNA molecules has become a reality thanks to major advances in single molecule pulling experiments. Although the unfolding p…