285 citations · 685 across the 12 of their papers we have counts for
4 papers · 1 filter
Gains in Power from Structured Two-Sample Tests of Means on Graphs
Laurent Jacob, Pierre Neuvial, Sandrine Dudoit
We consider multivariate two-sample tests of means, where the location shift between the two populations is expected to be related to a known graph structure. An important applicat…
Virtual screening of GPCRs: an in silico chemogenomics approach
Laurent Jacob, Brice Hoffmann, Véronique Stoven +1
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. \textit{In silico} prediction of interactions between GPCRs and small molec…
Kernel methods for in silico chemogenomics
Laurent Jacob, Jean-Philippe Vert
Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used…
Epitope prediction improved by multitask support vector machines
Laurent Jacob, Jean-Philippe Vert
Motivation: In silico methods for the prediction of antigenic peptides binding to MHC class I molecules play an increasingly important role in the identification of T-cell epitopes…