activity
20062014
most citedManipulation of conformational change in proteins by single residue perturbations

163 citations · 271 across the 14 of their papers we have counts for

collaborators

14 papers

q-bio.BM2014

Relative Mobility of Human Transferrin Domains Accounts for Its Efficient Recognition and Recycling

Haleh Abdizadeh, Ali Rana Atilgan, Canan Atilgan

Human serum transferrin (hTf) transports ferric ions in the blood stream and inflamed mucosal surfaces with high affinity and delivers them to cells via receptor mediated endocytos…

q-bio.BM2014

Protonation States of Remote Residues Affect Binding-Release Dynamics of the Ligand but not the Conformation of apo Ferric Binding Protein

Gokce Guven, Ali Rana Atilgan, Canan Atilgan

We have studied the apo (Fe3+ free) form of periplasmic ferric binding protein (FbpA) under different conditions and we have monitored the changes in the binding and release dynami…

cond-mat.soft2012★ 1 cited

On modifying properties of polymeric melts by nanoscopic particles

Canan Atilgan, Ibrahim Inanc, Ali Rana Atilgan

We study geometric and energetic factors that partake in modifying properties of polymeric melts via inserting well-dispersed nanoscopic particles (NP). Model systems are polybutad…

physics.bio-ph2011

Subtle pH differences trigger single residue motions for moderating conformations of calmodulin

Ali Rana Atilgan, Ayse Ozlem Aykut, Canan Atilgan

This study reveals the essence of ligand recognition mechanisms by which calmodulin (CaM) controls a variety of Ca2+ signaling processes. We study eight forms of calcium-loaded CaM…

cond-mat.dis-nn2010★ 18 cited

Assortative Mixing in Close-Packed Spatial Networks

Deniz Turgut, Ali Rana Atilgan, Canan Atilgan

A general relation for the dependence of nearest neighbor degree correlations on degree is derived. Dependence of local clustering on degree is shown to be the sole determining fac…

q-bio.BM2010★ 163 cited

Manipulation of conformational change in proteins by single residue perturbations

C Atilgan, Z N Gerek, S B Ozkan +1

Using the perturbation-response scanning (PRS) technique, we study a set of 23 proteins that display a variety of conformational motions upon ligand binding (e.g. shear, hinge, all…