2 papers
q-bio.BM2026
Towards coevolution-aware ancestral sequence reconstruction
Alya Zeinaty, Leonardo di Bari, Saverio Rossi +3
Ancestral sequence reconstruction (ASR) is a powerful approach for studying molecular evolution and the emergence of protein function. Yet most ASR methods assume that sites evolve…
q-bio.PE2024
Eco-evolutionary dynamics of adapting pathogens and host immunity
Pierre Barrat-Charlaix, Richard A. Neher
As pathogens spread in a population of hosts, immunity is built up and the pool of susceptible individuals is depleted. This generates selective pressure, to which many human RNA v…