5 papers
Two-Stage Fine-Tuning for Protein Sequence Generation with Targeted Amino-Acid Composition
Violeta Basten-Romero, Rubén Muñoz-Tafalla, Anna MarÃa DÃaz-Rovira +3
Protein language models are standard priors for biological sequence generation, but steering them toward explicit distributional design targets remains largely unexplored. We study…
Effective Resistance Rewiring: A Simple Topological Correction for Over-Squashing
Bertran Miquel-Oliver, Manel Gil-Sorribes, Victor Guallar +1
Graph Neural Networks struggle to capture long-range dependencies due to over-squashing, where information from exponentially growing neighborhoods must pass through a small number…
TopoBench: A Framework for Benchmarking Topological Deep Learning
Lev Telyatnikov, Guillermo Bernardez, Marco Montagna +34
This work introduces TopoBench, an open-source library designed to standardize benchmarking and accelerate research in topological deep learning (TDL). TopoBench decomposes TDL int…
Character-level Tokenizations as Powerful Inductive Biases for RNA Foundational Models
Adrián Morales-Pastor, Raquel Vázquez-Reza, MiÅosz Wieczór +5
RNA is a vital biomolecule with numerous roles and functions within cells, and interest in targeting it for therapeutic purposes has grown significantly in recent years. However, f…
ICML Topological Deep Learning Challenge 2024: Beyond the Graph Domain
Guillermo Bernárdez, Lev Telyatnikov, Marco Montagna +70
This paper describes the 2nd edition of the ICML Topological Deep Learning Challenge that was hosted within the ICML 2024 ELLIS Workshop on Geometry-grounded Representation Learnin…