72 citations · 239 across the 14 of their papers we have counts for
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stat.AP2011★ 44 cited
Response-adaptive dose-finding under model uncertainty
Björn Bornkamp, Frank Bretz, Holger Dette +1
Dose-finding studies are frequently conducted to evaluate the effect of different doses or concentration levels of a compound on a response of interest. Applications include the in…
stat.AP2010★ 12 cited
Optimal designs for random effect models with correlated errors with applications in population pharmacokinetics
Holger Dette, Andrey Pepelyshev, Tim Holland-Letz
We consider the problem of constructing optimal designs for population pharmacokinetics which use random effect models. It is common practice in the design of experiments in such s…