3 papers
stat.AP2025
Evaluating amyloid-beta as a surrogate endpoint in trials of anti-amyloid drugs in Alzheimer's disease: a Bayesian meta-analysis
Sa Ren, Janharpreet Singh, Sandro Gsteiger +8
The use of amyloid-beta (A) clearance to support regulatory approvals of drugs in Alzheimer's disease (AD) remains controversial. We evaluate A as a potential trial-level sur…
quant-ph2023
A Set-Theoretic Metaphysics for Quantum Mechanics
Paul Tappenden
Set theory brought revolution to philosophy of mathematics and it can bring revolution to philosophy of physics too. All that stands in the way is the intuition that sets of physic…
stat.ME2023
Individual participant data from digital sources informed and improved precision in the evaluation of predictive biomarkers in Bayesian network meta-analysis
Chinyereugo M Umemneku-Chikere, Lorna Wheaton, Heather Poad +7
Objective: We aimed to develop a meta-analytic model for evaluation of predictive biomarkers and targeted therapies, utilising data from digital sources when individual participant…