2 papers
math.DS2026
Multiscale feedback drives viral evolution and epidemic dynamics
Juan C. Muñoz-Sánchez, J. Tomás Lázaro, Josep Sardanyés +1
We introduce a minimal multiscale framework that links within-host virus dynamics to population-level SIRS epidemiology through explicit, bidirectional coupling. At the microscopic…
math.DS2024
Quasineutral multistability in an epidemiological-like model for defective-helper betacoronavirus infection in cell cultures
Juan C. Muñoz-Sánchez, J. Tomás Lázaro, Julia Hillung +3
It is well known that, during replication, RNA viruses spontaneously generate defective viral genomes (DVGs). DVGs are unable to complete an infectious cycle autonomously, and depe…