41 citations · 58 across the 4 of their papers we have counts for
3 papers · 1 filter
Optimal flux states, reaction replaceability and response to knockouts in the human red blood cell
A. De Martino, D. Granata, E. Marinari +2
Characterizing the capabilities, criticalities and response to perturbations of genome-scale metabolic networks is a basic problem with important applications. A key question conce…
Identifying essential genes in E. coli from a metabolic optimization principle
C. Martelli, A. De Martino, E. Marinari +2
Understanding the organization of reaction fluxes in cellular metabolism from the stoichiometry and the topology of the underlying biochemical network is a central issue in systems…
On the role of conserved moieties in shaping the robustness and production capabilities of reaction networks
Andrea De Martino, Carlotta Martelli, Francesco A. Massucci
We study a simplified, solvable model of a fully-connected metabolic network with constrained quenched disorder to mimic the conservation laws imposed by stoichiometry on chemical…