8 citations · 10 across the 4 of their papers we have counts for
4 papers
From Theory to Therapy: Reframing SBDD Model Evaluation via Practical Metrics
Bowen Gao, Haichuan Tan, Yanwen Huang +5
Recent advancements in structure-based drug design (SBDD) have significantly enhanced the efficiency and precision of drug discovery by generating molecules tailored to bind specif…
Rethinking Specificity in SBDD: Leveraging Delta Score and Energy-Guided Diffusion
Bowen Gao, Minsi Ren, Yuyan Ni +5
In the field of Structure-based Drug Design (SBDD), deep learning-based generative models have achieved outstanding performance in terms of docking score. However, further study sh…
Delta Score: Improving the Binding Assessment of Structure-Based Drug Design Methods
Minsi Ren, Bowen Gao, Bo Qiang +1
Structure-based drug design (SBDD) stands at the forefront of drug discovery, emphasizing the creation of molecules that target specific binding pockets. Recent advances in this ar…
DrugCLIP: Contrastive Protein-Molecule Representation Learning for Virtual Screening
Bowen Gao, Bo Qiang, Haichuan Tan +6
Virtual screening, which identifies potential drugs from vast compound databases to bind with a particular protein pocket, is a critical step in AI-assisted drug discovery. Traditi…