1 citations · 2 across the 3 of their papers we have counts for
3 papers
Confidence intervals for adaptive trial designs II: Case study and practical guidance
David S. Robertson, Thomas Burnett, Babak Choodari-Oskooei +4
In adaptive clinical trials, the conventional confidence interval (CI) for a treatment effect is prone to undesirable properties such as undercoverage and potential inconsistency w…
Confidence intervals for adaptive trial designs I: A methodological review
David S. Robertson, Thomas Burnett, Babak Choodari-Oskooei +4
Regulatory guidance notes the need for caution in the interpretation of confidence intervals (CIs) constructed during and after an adaptive clinical trial. Conventional CIs of the…
The use of restricted mean survival time to estimate treatment effect under model misspecification, a simulation study
Emily Alger, David S. Robertson, Abigail J. Burdon
The use of the non-parametric Restricted Mean Survival Time endpoint (RMST) has grown in popularity as trialists look to analyse time-to-event outcomes without the restrictions of…