most citedRethinking Specificity in SBDD: Leveraging Delta Score and Energy-Guided Diffusion

2 citations · 3 across the 5 of their papers we have counts for

collaborators

5 papers

cs.LG20241 cited

Pre-training with Fractional Denoising to Enhance Molecular Property Prediction

Yuyan Ni, Shikun Feng, Xin Hong +5

Deep learning methods have been considered promising for accelerating molecular screening in drug discovery and material design. Due to the limited availability of labelled data, v…

q-bio.BM20242 cited

Rethinking Specificity in SBDD: Leveraging Delta Score and Energy-Guided Diffusion

Bowen Gao, Minsi Ren, Yuyan Ni +5

In the field of Structure-based Drug Design (SBDD), deep learning-based generative models have achieved outstanding performance in terms of docking score. However, further study sh…

cs.LG2024

Contextual Molecule Representation Learning from Chemical Reaction Knowledge

Han Tang, Shikun Feng, Bicheng Lin +4

In recent years, self-supervised learning has emerged as a powerful tool to harness abundant unlabelled data for representation learning and has been broadly adopted in diverse are…

cs.IT2023

Elastic Information Bottleneck

Yuyan Ni, Yanyan Lan, Ao Liu +1

Information bottleneck is an information-theoretic principle of representation learning that aims to learn a maximally compressed representation that preserves as much information…

q-bio.BM2023

Sliced Denoising: A Physics-Informed Molecular Pre-Training Method

Yuyan Ni, Shikun Feng, Wei-Ying Ma +2

While molecular pre-training has shown great potential in enhancing drug discovery, the lack of a solid physical interpretation in current methods raises concerns about whether the…