1 citations · 1 across the 5 of their papers we have counts for
5 papers
Constructing Lower-Bounds for CTL Escape Rates in Early HIV and SIV Infection
Sivan Leviyang
Intrahost simian immunodeficiency virus (SIV) evolution is marked by repeated viral escape from cytotoxic T-lymphocyte (CTLs) response. Typically, the first such CTL escape occurs…
Computational Inference Methods for HIV-1 Selective Sweeps Shaped by Early Cytotoxic T-Lymphocyte Response
Sivan Leviyang
In this work we develop a stochastic model of acute HIV infection, based on the well-known standard model, that allows us to simulate the complex mutation pathways of HIV escape fr…
The Coalescence of Intrahost HIV Lineages Under Symmetric CTL Attack
Sivan Leviyang
Cytotoxic T lymphocytes (CTLs) are immune system cells that are thought to play an important role in controlling HIV infection. We develop a stochastic ODE model of HIV-CTL interac…
Analysis of a Stochastic Predator-Prey Model with Applications to Intrahost HIV Genetic Diversity
Sivan Leviyang
During an infection, HIV experiences strong selection by immune system T cells. Recent experimental work has shown that MHC escape mutations form an important pathway for HIV to av…
The Distribution of Fst and other Genetic Statistics for a Class of Population Structure Models
Sivan Leviyang
We examine genetic statistics used in the study of structured populations. In a 1999 paper, Wakeley observed that the coalescent process associated with the finite island model can…