237 citations · 379 across the 7 of their papers we have counts for
7 papers · 1 filter
Intronic Alus Influence Alternative Splicing
Galit Lev-Maor, Oren Ram, Eddo Kim +4
Examination of the human transcriptome reveals higher levels of RNA editing than in any other organism tested to date. This is indicative of extensive double-stranded RNA (dsRNA) f…
The Alternative Choice of Constitutive Exons throughout Evolution
Galit Lev-Maor, Amir Goren, Noa Sela +6
Alternative cassette exons are known to originate from two processes exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which const…
TranspoGene and microTranspoGene: transposed elements influence on the transcriptome of seven vertebrates and invertebrates
Asaf Levy, Noa Sela, Gil Ast
Transposed elements (TEs) are mobile genetic sequences. During the evolution of eukaryotes TEs were inserted into active protein-coding genes, affecting gene structure, expression…
Comparative analysis of transposed element insertion within human and mouse genomes reveals Alu's unique role in shaping the human transcriptome
Noa Sela, Britta Mersch, Nurit Gal-Mark +3
Background: Transposed elements (TEs) have a substantial impact on mammalian evolution and are involved in numerous genetic diseases. We compared the impact of TEs on the human tra…
Transduplication resulted in the incorporation of two protein-coding sequences into the Turmoil-1 transposable element of C. elegans
Noa Sela, Adi Stern, Wojciech Makalowski +2
Transposable elements may acquire unrelated gene fragments into their sequences in a process called transduplication. Transduplication of protein-coding genes is common in plants,…
Biased exonization of transposed elements in duplicated genes: A lesson from the TIF-IA gene
Maayan Amit, Noa Sela, Hadas Keren +5
Background: Gene duplication and exonization of intronic transposed elements are two mechanisms that enhance genomic diversity. We examined whether there is less selection against…