131 citations · 230 across the 2 of their papers we have counts for
4 papers · 1 filter
PAKing up to the endothelium
Eva Maria Galan Moya, Armelle Le Guelte, Julie Gavard
Angiogenesis recapitulates the growth of blood vessels that progressively expand and remodel into a highly organized and stereotyped vascular network. During adulthood, endothelial…
Breaking the VE-cadherin bonds
Julie Gavard
Exchanges between the blood compartment and the surrounding tissues require a tight regulation by the endothelial barrier. Recent reports inferred that VE-cadherin, an endothelial…
Protein Kinase C-related Kinase and ROCK Are Required for Thrombin-induced Endothelial Cell Permeability Downstream from G{alpha}12/13 and G{alpha}11/q
Julie Gavard, J Silvio Gutkind
Increase in vascular permeability occurs under many physiological conditions and is central in diverse human pathologies. Thrombin is a pro-coagulant serine protease, which causes…
VE-cadherin and claudin-5: it takes two to tango
Julie Gavard, J Silvio Gutkind
Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5, which are key components of adherens and tight endothelial junctions, respectively. Emergi…