71 citations · 95 across the 3 of their papers we have counts for
3 papers
MotifBench: A standardized protein design benchmark for motif-scaffolding problems
Zhuoqi Zheng, Bo Zhang, Kieran Didi +5
The motif-scaffolding problem is a central task in computational protein design: Given the coordinates of atoms in a geometry chosen to confer a desired biochemical function (a mot…
Fast protein backbone generation with SE(3) flow matching
Jason Yim, Andrew Campbell, Andrew Y. K. Foong +8
We present FrameFlow, a method for fast protein backbone generation using SE(3) flow matching. Specifically, we adapt FrameDiff, a state-of-the-art diffusion model, to the flow-mat…
SE(3) diffusion model with application to protein backbone generation
Jason Yim, Brian L. Trippe, Valentin De Bortoli +4
The design of novel protein structures remains a challenge in protein engineering for applications across biomedicine and chemistry. In this line of work, a diffusion model over ri…