5 citations · 9 across the 4 of their papers we have counts for
4 papers
GraphVF: Controllable Protein-Specific 3D Molecule Generation with Variational Flow
Fang Sun, Zhihao Zhan, Hongyu Guo +2
Designing molecules that bind to specific target proteins is a fundamental task in drug discovery. Recent models leverage geometric constraints to generate ligand molecules that bi…
Wheat Head Counting by Estimating a Density Map with Convolutional Neural Networks
Hongyu Guo
Wheat is one of the most significant crop species with an annual worldwide grain production of 700 million tonnes. Assessing the production of wheat spikes can help us measure the…
T-Cell Receptor Optimization with Reinforcement Learning and Mutation Policies for Precesion Immunotherapy
Ziqi Chen, Martin Renqiang Min, Hongyu Guo +3
T cells monitor the health status of cells by identifying foreign peptides displayed on their surface. T-cell receptors (TCRs), which are protein complexes found on the surface of…
Over-training with Mixup May Hurt Generalization
Zixuan Liu, Ziqiao Wang, Hongyu Guo +1
Mixup, which creates synthetic training instances by linearly interpolating random sample pairs, is a simple and yet effective regularization technique to boost the performance of…