2 papers
stat.ME2026
A Practical Framework for Sensitivity Analysis in Externally Controlled Trials: An Illustration with a Bayesian Hybrid Evidence Synthesis Case Study
Xuemin Gu, Kitty Guo, Jane Zhang
Externally controlled trials (ECTs), including single-arm studies augmented with historical data and hybrid randomized designs with partial external augmentation, are increasingly…
stat.ME2025
An Integrated and Coherent Framework for Point Estimation and Hypothesis Testing with Concurrent Controls in Platform Trials
Tianyu Zhan, Jane Zhang, Lei Shu +1
A platform trial with a master protocol provides an infrastructure to ethically and efficiently evaluate multiple treatment options in multiple diseases. Given that certain study d…